| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lymphocyte antigen 96 |
|---|
| Ligand | BDBM50239336 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1665929 (CHEMBL4015725) |
|---|
| IC50 | 10000±n/a nM |
|---|
| Citation |  Sestito, SE; Facchini, FA; Morbioli, I; Billod, JM; Martin-Santamaria, S; Casnati, A; Sansone, F; Peri, F Amphiphilic Guanidinocalixarenes Inhibit Lipopolysaccharide (LPS)- and Lectin-Stimulated Toll-like Receptor 4 (TLR4) Signaling. J Med Chem60:4882-4892 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lymphocyte antigen 96 |
|---|
| Name: | Lymphocyte antigen 96 |
|---|
| Synonyms: | ESOP-1 | ESOP1 | ESOP1 | LY96 | LY96_HUMAN | Ly-96 | Lymphocyte antigen 96 | MD2 | Protein MD-2 | TLR4-MD2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 18551.39 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_107939 |
|---|
| Residue: | 160 |
|---|
| Sequence: | MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGL
LHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFS
FKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN
|
|
|
|---|
| BDBM50239336 |
|---|
| n/a |
|---|
| Name | BDBM50239336 |
|---|
| Synonyms: | CHEMBL4093531 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C60H96Cl4N12O4 |
|---|
| Mol. Mass. | 1191.294 |
|---|
| SMILES | Cl.Cl.Cl.Cl.CC(C)(C)c1cc2Cc3cc(cc(Cc4cc(cc(Cc5cc(cc(Cc(c1)c2OCCCNC(N)=N)c5OCCCNC(N)=N)C(C)(C)C)c4OCCCNC(N)=N)C(C)(C)C)c3OCCCNC(N)=N)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
