| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK4 |
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| Ligand | BDBM50239782 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1667065 (CHEMBL4016861) |
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| IC50 | 2.3±n/a nM |
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| Citation |  ElHady, AK; Abdel-Halim, M; Abadi, AH; Engel, M Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins. J Med Chem60:5377-5391 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK4 |
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| Name: | Dual specificity protein kinase CLK4 |
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| Synonyms: | CDC-like kinase 4 | CLK4_MOUSE | Clk4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.39 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1502248 |
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| Residue: | 481 |
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| Sequence: | MRHSKRTHCPDWDSRESWGHESYSGSHKRKRRSHSSTQENRHCKPHHQFKDSDCHYLEAR
CLNERDYRDRRYIDEYRNDYCEGYVPRHYHRDVESTYRIHCSKSSVRSRRSSPKRKRNRP
CASHQSHSKSHRRKRSRSIEDDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHG
MDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFE
LLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYV
VKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDV
WSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEH
SSAGRYVRRRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPARRITLDEALQHPFFDLLKR
K
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| BDBM50239782 |
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| n/a |
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| Name | BDBM50239782 |
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| Synonyms: | CHEMBL4082113 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16FNO2S |
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| Mol. Mass. | 329.389 |
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| SMILES | COc1ccc2sc(cc2c1)C(=O)N(C)Cc1cccc(F)c1 |
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| Structure | 
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