| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50240230 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1667830 (CHEMBL4017718) |
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| Ki | 13±n/a nM |
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| Citation |  Salvino, JM; Srikanth, YVV; Lou, R; Oyer, HM; Chen, N; Kim, FJ Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer. Bioorg Med Chem Lett27:2216-2220 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50240230 |
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| n/a |
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| Name | BDBM50240230 |
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| Synonyms: | CHEMBL4092687 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20FN3O2 |
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| Mol. Mass. | 317.358 |
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| SMILES | COc1ccc(NC(=N)NCCCOc2ccc(F)cc2)cc1 |
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| Structure | 
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