| Reaction Details |
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 | Report a problem with these data |
| Target | ELAV-like protein 1 |
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| Ligand | BDBM50240686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1668500 (CHEMBL4018388) |
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| IC50 | 6210±n/a nM |
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| Citation |  Nasti, R; Rossi, D; Amadio, M; Pascale, A; Unver, MY; Hirsch, AKH; Collina, S Compounds Interfering with Embryonic Lethal Abnormal Vision (ELAV) Protein-RNA Complexes: An Avenue for Discovering New Drugs. J Med Chem60:8257-8267 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ELAV-like protein 1 |
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| Name: | ELAV-like protein 1 |
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| Synonyms: | ELAV1_HUMAN | ELAVL1 | HUR | Hu-antigen R |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36102.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_654855 |
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| Residue: | 326 |
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| Sequence: | MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHS
LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQK
DVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPIT
VKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNA
SSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAM
AIASLNGYRLGDKILQVSFKTNKSHK
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| BDBM50240686 |
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| n/a |
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| Name | BDBM50240686 |
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| Synonyms: | CHEMBL4095140 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H16ClN5O2S |
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| Mol. Mass. | 449.913 |
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| SMILES | COc1ccc(cc1)-c1c(C#N)c(N)nc(SCC(=O)Nc2ccc(Cl)cc2)c1C#N |
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| Structure | 
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