| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM50197883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1670053 (CHEMBL4019941) |
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| Kd | 278±n/a nM |
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| Citation |  Smith, TP; Windsor, IW; Forest, KT; Raines, RT Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation. J Med Chem60:7820-7834 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM50197883 |
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| n/a |
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| Name | BDBM50197883 |
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| Synonyms: | CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Compound Tafamidis | Vyndaqel |
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| Type | Small organic molecule |
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| Emp. Form. | C14H7Cl2NO3 |
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| Mol. Mass. | 308.116 |
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| SMILES | OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 |
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| Structure | 
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