| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase A |
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| Ligand | BDBM50242961 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1672428 (CHEMBL4022457) |
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| Ki | 47500±n/a nM |
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| Citation |  Park, JY; Hwan Lim, S; Ram Kim, B; Jae Jeong, H; Kwon, HJ; Song, GY; Bae Ryu, Y; Song Lee, W Sialidase inhibitory activity of diarylnonanoid and neolignan compounds extracted from the seeds of Myristica fragrans. Bioorg Med Chem Lett27:3060-3064 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase A |
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| Name: | Sialidase A |
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| Synonyms: | NANA_STREE | Neuraminidase A (NanA) | Sialidase A | nanA |
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| Type: | Enzyme |
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| Mol. Mass.: | 114737.08 |
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| Organism: | Streptococcus pneumoniae |
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| Description: | P62576; spr1536 |
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| Residue: | 1035 |
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| Sequence: | MSYFRNRDIDIERNSMNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASEQ
PLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLENVET
VIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSSATKKD
EYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAELPKGRVR
LYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTVYNRALTPEE
VQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIPALLKTDKGTLI
AGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASDPSIGSPVNIDMVL
VQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILYREGEKGAYTIRENGT
VYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTNKTSPFRIAKDSYLWMSY
SDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPHKGRILIPVYTTNNVSHLNG
SQSSRIIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMNNRRAQNTESTVVQLNNGDVKL
FMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQMSAIHTMHEGKEYIILSNAGGPK
RENGMVHLARVEENGELTWLKHNPIQKGEFAYNSLQELGNGEYGILYEHTEKGQNAYTLS
FRKFNWDFLSKDLISPTEAKVKRTREMGKGVIGLEFDSEVLVNKAPTLQLANGKTARFMT
QYDTKTLLFTVDSEDMGQKVTGLAEGAIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEY
TGPLGTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEF
TGGVNGTEPAVHEIAEYKGSDSLVTLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLT
AFFLGLFTLGKKREQ
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| BDBM50242961 |
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| n/a |
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| Name | BDBM50242961 |
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| Synonyms: | CHEMBL4091275 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22O5 |
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| Mol. Mass. | 354.3964 |
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| SMILES | COc1cc(cc2OCOc12)[C@H]1Oc2c(cc(\C=C\C)cc2OC)[C@@H]1C |r| |
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| Structure | 
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