| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B-cell lymphoma 6 protein |
|---|
| Ligand | BDBM50247637 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1678302 (CHEMBL4028445) |
|---|
| IC50 | 212000±n/a nM |
|---|
| Citation |  Gilberg, E; Gütschow, M; Bajorath, J X-ray Structures of Target-Ligand Complexes Containing Compounds with Assay Interference Potential. J Med Chem61:1276-1284 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B-cell lymphoma 6 protein |
|---|
| Name: | B-cell lymphoma 6 protein |
|---|
| Synonyms: | B-cell lymphoma 5 protein | B-cell lymphoma 6 protein | BCL-5 | BCL-6 | BCL5 | BCL6 | BCL6_HUMAN | BCoR-BCL6 | LAZ3 | Protein LAZ-3 | ZBTB27 | ZNF51 | Zinc finger and BTB domain-containing protein 27 | Zinc finger protein 51 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 78866.89 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_117695 |
|---|
| Residue: | 706 |
|---|
| Sequence: | MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSI
FTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDT
CRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAF
APSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPG
EYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKAS
KEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASG
SPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEP
ENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGS
QSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQT
HSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEK
PYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHC
EKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC
|
|
|
|---|
| BDBM50247637 |
|---|
| n/a |
|---|
| Name | BDBM50247637 |
|---|
| Synonyms: | CHEMBL4069658 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H11BrN2O5S2 |
|---|
| Mol. Mass. | 443.292 |
|---|
| SMILES | OC(=O)CC(N1C(=S)SC\C1=C1\C(=O)Nc2ccc(Br)cc12)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
