| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
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| Ligand | BDBM50250215 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1681317 |
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| EC50 | >3000±n/a nM |
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| Citation |  Palmer, D; Gonçalves, JPL; V Hansen, L; Wu, B; Hald, H; Schoffelen, S; Diness, F; Le Quement, ST; Nielsen, TE; Meldal, M Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists. J Med Chem60:8716-8730 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 3 |
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| Name: | Melanocortin receptor 3 |
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| Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36044.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41968 |
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| Residue: | 323 |
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| Sequence: | MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFREILCGCNGMNLG
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| BDBM50250215 |
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| n/a |
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| Name | BDBM50250215 |
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| Synonyms: | CHEMBL4091536 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H72N18O9S |
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| Mol. Mass. | 1077.265 |
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| SMILES | CC[C@@H](C)[C@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cn2cc(C[C@H](NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCSC)C(O)=O)nn2)NC(=O)[C@@H](N)CCCCN |r| |
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| Structure | 
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