| Reaction Details |
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 | Report a problem with these data |
| Target | dCTP pyrophosphatase 1 |
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| Ligand | BDBM50260217 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1693435 |
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| IC50 | 200±n/a nM |
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| Citation |  Llona-Minguez, S; Häggblad, M; Martens, U; Johansson, L; Sigmundsson, K; Lundbäck, T; Loseva, O; Jemth, AS; Lundgren, B; Jensen, AJ; Scobie, M; Helleday, T Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems. Bioorg Med Chem Lett27:3219-3225 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| dCTP pyrophosphatase 1 |
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| Name: | dCTP pyrophosphatase 1 |
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| Synonyms: | DCTP1_HUMAN | DCTPP1 | Deoxycytidine-triphosphatase 1 | XTP3TPA | dCTP pyrophosphatase 1 | dCTP pyrophosphatase 1 (DCTPP1) |
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| Type: | Protein |
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| Mol. Mass.: | 18673.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H773 |
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| Residue: | 170 |
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| Sequence: | MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLAL
VGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLS
KMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST
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| BDBM50260217 |
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| n/a |
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| Name | BDBM50260217 |
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| Synonyms: | CHEMBL4062129 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N5O2 |
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| Mol. Mass. | 337.3758 |
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| SMILES | Cc1c(C)n2c(nc3n(C)c(=O)[nH]c(=O)c23)n1Cc1ccc(C)cc1 |
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| Structure | 
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