| Reaction Details |
|---|
 | Report a problem with these data |
| Target | dCTP pyrophosphatase 1 |
|---|
| Ligand | BDBM50260234 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1693435 |
|---|
| IC50 | 190±n/a nM |
|---|
| Citation |  Llona-Minguez, S; Häggblad, M; Martens, U; Johansson, L; Sigmundsson, K; Lundbäck, T; Loseva, O; Jemth, AS; Lundgren, B; Jensen, AJ; Scobie, M; Helleday, T Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems. Bioorg Med Chem Lett27:3219-3225 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| dCTP pyrophosphatase 1 |
|---|
| Name: | dCTP pyrophosphatase 1 |
|---|
| Synonyms: | DCTP1_HUMAN | DCTPP1 | Deoxycytidine-triphosphatase 1 | XTP3TPA | dCTP pyrophosphatase 1 | dCTP pyrophosphatase 1 (DCTPP1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 18673.58 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9H773 |
|---|
| Residue: | 170 |
|---|
| Sequence: | MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLAL
VGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLS
KMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST
|
|
|
|---|
| BDBM50260234 |
|---|
| n/a |
|---|
| Name | BDBM50260234 |
|---|
| Synonyms: | CHEMBL4060941 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18ClN3O |
|---|
| Mol. Mass. | 315.797 |
|---|
| SMILES | CCCc1c(C)[nH]c2c(c(C)nn2c1=O)-c1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
