Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50260244 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_1693459 |
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Ki | 3.7±n/a nM |
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Citation | Kutsumura, N; Koyama, Y; Nagumo, Y; Nakajima, R; Miyata, Y; Yamamoto, N; Saitoh, T; Yoshida, N; Iwata, S; Nagase, H Antitrichomonal activity of? opioid receptor antagonists, 7-benzylidenenaltrexone derivatives. Bioorg Med Chem25:4375-4383 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM50260244 |
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n/a |
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Name | BDBM50260244 |
Synonyms: | CHEMBL3632690 |
Type | Small organic molecule |
Emp. Form. | C29H32N2O4 |
Mol. Mass. | 472.5754 |
SMILES | [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)C\C(=C/c1ccc(cc1)N(C)C)C2=O)ccc3O |r,TLB:10:9:17:6.4.5| |
Structure |
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