Reaction Details |
| Report a problem with these data |
Target | G-protein coupled receptor 4 |
---|
Ligand | BDBM50260328 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_1693531 |
---|
IC50 | >20000±n/a nM |
---|
Citation | Miltz, W; Velcicky, J; Dawson, J; Littlewood-Evans, A; Ludwig, MG; Seuwen, K; Feifel, R; Oberhauser, B; Meyer, A; Gabriel, D; Nash, M; Loetscher, P Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis. Bioorg Med Chem25:4512-4525 (2017) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
G-protein coupled receptor 4 |
---|
Name: | G-protein coupled receptor 4 |
Synonyms: | G-protein coupled receptor 4 | GPR4_MOUSE | Gpr4 |
Type: | PROTEIN |
Mol. Mass.: | 41117.52 |
Organism: | Mus musculus |
Description: | ChEMBL_117369 |
Residue: | 365 |
Sequence: | MDNSTGTGEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVRQHNELGVYLMN
LSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYSNIYISIAFLCCISVDRYLA
VAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMERWV
AWMNLYRVFVGFLFPWALMLLCYRGILRAVQSSVSTERQEKVKIKRLALSLIAIVLVCFA
PYHALLLSRSAVYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVA
KALHNLLRFLASNKPQEMANASLTLETPLTSKRSTTGKSSGAVWAVPPTAQGDQVPLKVL
LPPAQ
|
|
|
BDBM50260328 |
---|
n/a |
---|
Name | BDBM50260328 |
Synonyms: | CHEMBL4090675 |
Type | Small organic molecule |
Emp. Form. | C25H33N5 |
Mol. Mass. | 403.563 |
SMILES | CCc1nc2cccnc2n1Cc1ccc(\C=C\CN2CCN(CC2)C(C)C)cc1 |
Structure |
|