| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM22886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_86895 (CHEMBL698405) |
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| Ki | 60±n/a nM |
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| Citation |  Timmerman, H Histamine H3 ligands: just pharmacological tools or potential therapeutic agents? J Med Chem33:4-11 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM22886 |
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| n/a |
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| Name | BDBM22886 |
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| Synonyms: | 3-[(2R)-1-(1H-imidazol-5-yl)propan-2-yl]-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine | CHEMBL275803 | N-[2-(1H-Imidazol-4-yl)-1-methyl-ethyl]-N'-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine(R-sopromidine) | R-(-)-Sopromidine |
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| Type | Small organic molecule |
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| Emp. Form. | C14H23N7S |
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| Mol. Mass. | 321.444 |
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| SMILES | C[C@H](Cc1cnc[nH]1)N=C(N)NCCSCc1[nH]cnc1C |w:9.10| |
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| Structure | 
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