| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
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| Ligand | BDBM50263940 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1698355 (CHEMBL4049245) |
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| IC50 | >30000±n/a nM |
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| Citation |  Sekiguchi, H; Kuroyanagi, T; Rhainds, D; Kobayashi, K; Kobayashi, Y; Ohno, H; Heveker, N; Akaji, K; Fujii, N; Oishi, S Structure-Activity Relationship Study of Cyclic Pentapeptide Ligands for Atypical Chemokine Receptor 3 (ACKR3). J Med Chem61:3745-3751 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 4 |
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| Name: | C-X-C chemokine receptor type 4 |
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| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4) | CD_antigen=CD184 | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_HUMAN | FB22 | Fusin | HM89 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | NPYRL | SDF-1 receptor | Stromal cell-derived factor 1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39754.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P61073 |
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| Residue: | 352 |
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| Sequence: | MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVI
LVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNL
YSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA
DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKT
TVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPI
LYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
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| BDBM50263940 |
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| n/a |
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| Name | BDBM50263940 |
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| Synonyms: | CHEMBL4084265 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H48N10O6 |
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| Mol. Mass. | 764.8725 |
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| SMILES | [H][C@@]12CCCN1C(=O)[C@H](Cc1ccc3ccccc3c1)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](Cc1ccc(O)cc1)NC2=O |r| |
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| Structure | 
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