| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 4 |
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| Ligand | BDBM50265897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1700320 (CHEMBL4051302) |
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| EC50 | 78±n/a nM |
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| Citation |  McCoull, W; Bailey, A; Barton, P; Birch, AM; Brown, AJ; Butler, HS; Boyd, S; Butlin, RJ; Chappell, B; Clarkson, P; Collins, S; Davies, RM; Ertan, A; Hammond, CD; Holmes, JL; Lenaghan, C; Midha, A; Morentin-Gutierrez, P; Moore, JE; Raubo, P; Robb, G Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy. J Med Chem60:3187-3197 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 4 |
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| Name: | Free fatty acid receptor 4 |
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| Synonyms: | FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42256.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1508994 |
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| Residue: | 377 |
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| Sequence: | MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA
RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
ILTDTSVKRNDLSIISG
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| BDBM50265897 |
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| n/a |
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| Name | BDBM50265897 |
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| Synonyms: | CHEMBL4096579 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21FN2O3 |
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| Mol. Mass. | 416.4442 |
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| SMILES | COc1nn(-c2ccc(C)cc2)c2cc(cc(F)c12)-c1ccc(cc1)[C@H]1C[C@@H]1C(O)=O |r| |
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| Structure | 
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