| Reaction Details |
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 | Report a problem with these data |
| Target | Free fatty acid receptor 1 |
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| Ligand | BDBM50265868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1700322 (CHEMBL4051304) |
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| EC50 | >100000±n/a nM |
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| Citation |  McCoull, W; Bailey, A; Barton, P; Birch, AM; Brown, AJ; Butler, HS; Boyd, S; Butlin, RJ; Chappell, B; Clarkson, P; Collins, S; Davies, RM; Ertan, A; Hammond, CD; Holmes, JL; Lenaghan, C; Midha, A; Morentin-Gutierrez, P; Moore, JE; Raubo, P; Robb, G Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy. J Med Chem60:3187-3197 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Free fatty acid receptor 1 |
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| Name: | Free fatty acid receptor 1 |
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| Synonyms: | FFAR1_MOUSE | Ffar1 | Gpr40 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31818.80 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1454431 |
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| Residue: | 300 |
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| Sequence: | MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLP
LKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRP
RYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSAR
PARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPY
NASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK
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| BDBM50265868 |
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| n/a |
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| Name | BDBM50265868 |
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| Synonyms: | CHEMBL4071228 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19N3O2 |
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| Mol. Mass. | 357.4052 |
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| SMILES | Cc1nn(-c2ccccn2)c2cc(ccc12)-c1cccc(CCC(O)=O)c1 |
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| Structure | 
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