Reaction Details |
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Target | Free fatty acid receptor 4 |
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Ligand | BDBM50265896 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1700349 (CHEMBL4051331) |
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EC50 | 1000±n/a nM |
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Citation | McCoull, W; Bailey, A; Barton, P; Birch, AM; Brown, AJ; Butler, HS; Boyd, S; Butlin, RJ; Chappell, B; Clarkson, P; Collins, S; Davies, RM; Ertan, A; Hammond, CD; Holmes, JL; Lenaghan, C; Midha, A; Morentin-Gutierrez, P; Moore, JE; Raubo, P; Robb, G Indazole-6-phenylcyclopropylcarboxylic Acids as Selective GPR120 Agonists with in Vivo Efficacy. J Med Chem60:3187-3197 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Free fatty acid receptor 4 |
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Name: | Free fatty acid receptor 4 |
Synonyms: | FFAR4_MOUSE | Ffar4 | Free fatty acid receptor 4 | G-protein coupled receptor GT01 | Gpr120 | O3far1 | Omega-3 fatty acid receptor 1 |
Type: | PROTEIN |
Mol. Mass.: | 40828.60 |
Organism: | Mus musculus |
Description: | ChEMBL_1454435 |
Residue: | 361 |
Sequence: | MSPECAQTTGPGPSHTLDQVNRTHFPFFSDVKGDHRLVLSVVETTVLGLIFVVSLLGNVC
ALVLVARRRRRGATASLVLNLFCADLLFTSAIPLVLVVRWTEAWLLGPVVCHLLFYVMTM
SGSVTILTLAAVSLERMVCIVRLRRGLSGPGRRTQAALLAFIWGYSALAALPLCILFRVV
PQRLPGGDQEIPICTLDWPNRIGEISWDVFFVTLNFLVPGLVIVISYSKILQITKASRKR
LTLSLAYSESHQIRVSQQDYRLFRTLFLLMVSFFIMWSPIIITILLILIQNFRQDLVIWP
SLFFWVVAFTFANSALNPILYNMSLFRNEWRKIFCCFFFPEKGAIFTDTSVRRNDLSVIS
S
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BDBM50265896 |
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n/a |
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Name | BDBM50265896 |
Synonyms: | CHEMBL4070359 |
Type | Small organic molecule |
Emp. Form. | C23H19FN4O2 |
Mol. Mass. | 402.421 |
SMILES | Cc1nn(-c2ccc(C)cn2)c2cc(ncc12)-c1ccc(cc1F)[C@H]1C[C@@H]1C(O)=O |r| |
Structure |
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