| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon-like peptide 1 receptor |
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| Ligand | BDBM50241203 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1701195 (CHEMBL4052177) |
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| EC50 | 0.0005±n/a nM |
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| Citation |  Evers, A; Haack, T; Lorenz, M; Bossart, M; Elvert, R; Henkel, B; Stengelin, S; Kurz, M; Glien, M; Dudda, A; Lorenz, K; Kadereit, D; Wagner, M Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists. J Med Chem60:4293-4303 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon-like peptide 1 receptor |
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| Name: | Glucagon-like peptide 1 receptor |
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| Synonyms: | GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R_MOUSE | Glp1r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53042.00 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_598679 |
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| Residue: | 463 |
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| Sequence: | MASTPSLLRLALLLLGAVGRAGPRPQGTTVSLSETVQKWREYRRQCQRFLTEAPLLATGL
FCNRTFDDYACWPDGPPGSFVNVSCPWYLPWASSVLQGHVYRFCTAEGLWLHKDNSSLPW
RDLSECEESKRGERNFPEEQLLSLYIIYTVGYALSFSALVIASAILVGFRHLHCTRNYIH
LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLGCRLVFLLMQYCVAAN
YYWLLVEGVYLYTLLAFSVFSEQRIFKLYLSIGWGVPLLFVIPWGIVKYLYEDEGCWTRN
SNMNYWLIIRLPILFAIGVNFLIFIRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQMEFRKCWERW
RLEHLNIQRDCSMKPLKCPTSSVSSGATVGSSVYAATCQSSYS
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| BDBM50241203 |
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| n/a |
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| Name | BDBM50241203 |
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| Synonyms: | CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPPS-NH2 | exenatide | exendin-4 |
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| Type | Small organic molecule |
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| Emp. Form. | C184H282N50O60S |
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| Mol. Mass. | 4186.572 |
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| SMILES | n/a |
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| Structure | 
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