| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gastrin/cholecystokinin type B receptor |
|---|
| Ligand | BDBM50011966 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_48267 |
|---|
| IC50 | 67±n/a nM |
|---|
| Citation |  Yu, MJ; Thrasher, KJ; McCowan, JR; Mason, NR; Mendelsohn, LG Quinazolinone cholecystokinin-B receptor ligands. J Med Chem34:1505-8 (1991) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gastrin/cholecystokinin type B receptor |
|---|
| Name: | Gastrin/cholecystokinin type B receptor |
|---|
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49196.59 |
|---|
| Organism: | MOUSE |
|---|
| Description: | Cholecystokinin A CCKBR MOUSE::P56481 |
|---|
| Residue: | 453 |
|---|
| Sequence: | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITL
YAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTF
IFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWL
LSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGL
ISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCY
VQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANT
WRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPR
ARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
|
|
|
|---|
| BDBM50011966 |
|---|
| n/a |
|---|
| Name | BDBM50011966 |
|---|
| Synonyms: | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-cyclopentyloxy-phenyl)-3H-quinazolin-4-one | CHEMBL287740 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H26BrN3O2 |
|---|
| Mol. Mass. | 528.44 |
|---|
| SMILES | Brc1ccc2[nH]cc(CCc3nc4ccccc4c(=O)n3-c3cccc(OC4CCCC4)c3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
