| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 5A |
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| Ligand | BDBM50267886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1704105 (CHEMBL4055338) |
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| IC50 | 8300±n/a nM |
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| Citation |  Elumalai, N; Natarajan, K; Berg, T Halogen-substituted catechol bisphosphates are potent and selective inhibitors of the transcription factor STAT5b. Bioorg Med Chem25:3871-3882 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 5A |
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| Name: | Signal transducer and activator of transcription 5A |
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| Synonyms: | STA5A_HUMAN | STAT5 | STAT5A | Signal transducer and activator of transcription 5A | Transcription factor STAT5a (STAT5a) |
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| Type: | Protein |
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| Mol. Mass.: | 90643.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 794 |
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| Sequence: | MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQRLV
REANNCSSPAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPERNLWNLKPFTTRDFSIRSLADRL
GDLSYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVNASADAGGSSATY
MDQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRPMDSLDSRLS
PPAGLFTSARGSLS
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| BDBM50267886 |
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| n/a |
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| Name | BDBM50267886 |
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| Synonyms: | CHEMBL4093849 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21FN2O11P2 |
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| Mol. Mass. | 570.3549 |
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| SMILES | OP(O)(=O)Oc1ccc(CNC(=O)COc2ccc(cc2)C(=O)Nc2ccc(F)cc2)cc1OP(O)(O)=O |
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| Structure | 
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