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TargetGastrin-releasing peptide receptor
LigandBDBM50012318
Substrate/Competitorn/a
Meas. Tech.ChEMBL_206637 (CHEMBL810154)
IC50 1.4±n/a nM
Citation Heimbrook, DC; Saari, WS; Balishin, NL; Fisher, TW; Friedman, A; Kiefer, DM; Rotberg, NS; Wallen, JW; Oliff, A Gastrin releasing peptide antagonists with improved potency and stability. J Med Chem34:2102-7 (1991) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Gastrin-releasing peptide receptor
Name:Gastrin-releasing peptide receptor
Synonyms:GRP-R | GRP-preferring bombesin receptor | GRPR_MOUSE | Gastrin releasing peptide receptor | Gastrin-releasing peptide receptor | Grpr
Type:Enzyme Catalytic Domain
Mol. Mass.:43234.59
Organism:MOUSE
Description:Gastrin-Releasing peptide 0 MOUSE::P21729
Residue:384
Sequence:
MAPNNCSHLNLDVDPFLSCNDTFNQSLSPPKMDNWFHPGFIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMNRSHSTGRSTTCMT
SFKSTNPSATFSLINRNICHEGYV
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  Blast E-value cutoff:
BDBM50012318
n/a
NameBDBM50012318
Synonyms:2-{2-[2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-3-(1H-indol-3-yl)-propionylamino]-propionylamino}-N-{[2-(3H-imidazol-4-yl)-1-(1-isobutyl-pentylcarbamoyl)-ethylcarbamoyl]-methyl}-3-methyl-butyramide | CHEMBL294724
TypeSmall organic molecule
Emp. Form.C44H64N12O7
Mol. Mass.873.0552
SMILESCCCC[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(C)C
Structure
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