| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sialidase-1 |
|---|
| Ligand | BDBM50270444 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1708168 (CHEMBL4059401) |
|---|
| IC50 | 240000±n/a nM |
|---|
| Citation |  Guo, T; Dätwyler, P; Demina, E; Richards, MR; Ge, P; Zou, C; Zheng, R; Fougerat, A; Pshezhetsky, AV; Ernst, B; Cairo, CW Selective Inhibitors of Human Neuraminidase 3. J Med Chem61:1990-2008 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sialidase-1 |
|---|
| Name: | Sialidase-1 |
|---|
| Synonyms: | NANH | NEU1 | NEUR1_HUMAN | Sialidase 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 45463.28 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_960639 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM
EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST
WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS
WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW
RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD
TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET
VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
|
|
|
|---|
| BDBM50270444 |
|---|
| n/a |
|---|
| Name | BDBM50270444 |
|---|
| Synonyms: | CHEMBL4071732 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H22N4O9 |
|---|
| Mol. Mass. | 462.4101 |
|---|
| SMILES | [H][C@]1(OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)Cn1cc(nn1)-c1ccc(cc1)C(O)=O |r,c:3| |
|---|
| Structure | 
|
|---|
Search and Browse
