Ki Summary

Reaction Details

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Target

Alpha-xylosidase

Ligand

BDBM23406

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_1709226 (CHEMBL4119275)

IC50

1030000±n/a nM

Citation

Flores-Bocanegra, L; Gonz�lez-Andrade, M; Bye, R; Linares, E; Mata, R ?-Glucosidase Inhibitors from Salvia circinata. J Nat Prod80:1584-1593 (2017) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Alpha-xylosidase

Name:

Alpha-xylosidase

Synonyms:

3.2.1.177 | Alpha-glucosidase | Alpha-xylosidase | ERS852394_00763 | yicI

Type:

PROTEIN

Mol. Mass.:

77058.74

Organism:

Blautia obeum

Description:

ChEMBL_117769

Residue:

663

Sequence:

MIRKYRYGAPFDTEALTEKIETAEEAFPYGEISQKEGFAFTYIMDEDDIVYGLGESNRGI
NKRGYCYISNCTDDPIHTEDKRSLYGAHNFIIVSGKTTFGLFFDYPSKLTFDIGYTRMDT
LKVSCENADLDIYVIEGENAYDIVKQFRRVIGRSYIPPKFAFGFGQSRWGYTTKEDFRAV
AKGYRENHIPIDMIYMDIDYMQDFKDFTVNEKNFPDFPEFVKEMKDQELRLIPIIDAGVK
VEKGYEVYEEGVKNNYFCKREDGSDFVAAVWPGDTHFPDMLNPEARKWFGDKYRFLIDQG
IEGFWNDMNEPAIFYSSEGLAEAKEFAGEFAKDTEGKIHPWAMQAKMKDIVNSPEDYKRF
YHNVNGKKIRHDKVHNLFGYNMTRAAGEAFERIDPEKRFLMFSRSSYIGMHRYGGIWMGD
NKSWWSHILLNLKMLPSLNMCGFMYTGADLGGFGDDTTRDLLLRFLALGVFTPLMRDHAA
EGTREQECYQFENIEDFRSVINARYRLVPYLYSEYMKAALNDDMYFKPLGFVYPDDKMAI
RVEDQLMLGNEIMIAPVYEQNARGRYVYLPEEMKFIKFMPDGSISEEVLEKGVHYVDVAL
NEVPLFIRSGKCIPVAEAAECVKDIDTENMQLIGYEGSSYTLYEDDGIHKDYDKKENYRV
LTK

BDBM23406

n/a

Name

BDBM23406

Synonyms:

(3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol | Acarbose | US11292789, Acarbose

Type

Carbohydrate

Emp. Form.

C25H43NO18

Mol. Mass.

645.6048

SMILES

C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O |t:37|

Structure