| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50013534 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_52212 |
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| Ki | 42.0±n/a nM |
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| Citation |  Youssefyeh, RD; Magnien, E; Lee, TD; Chan, WK; Lin, CJ; Galemmo, RA; Johnson, WH; Tan, J; Campbell, HF; Huang, FC Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships. J Med Chem33:1186-94 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50013534 |
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| n/a |
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| Name | BDBM50013534 |
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| Synonyms: | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]-phenoxymethyl}-quinoline | 2-{3-[3-(1H-Tetrazol-5-yl)-propoxy]-phenoxymethyl}-quinoline (RG 7152) | CHEMBL418551 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N5O2 |
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| Mol. Mass. | 361.3972 |
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| SMILES | C(COc1cccc(OCc2ccc3ccccc3n2)c1)Cc1nnn[nH]1 |
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| Structure | 
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