| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50271568 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1711174 (CHEMBL4121223) |
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| Kd | 5129±n/a nM |
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| Citation |  Conroy, S; Kindon, ND; Glenn, J; Stoddart, LA; Lewis, RJ; Hill, SJ; Kellam, B; Stocks, MJ Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y J Med Chem61:3089-3113 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50271568 |
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| n/a |
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| Name | BDBM50271568 |
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| Synonyms: | CHEMBL4129299 |
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| Type | Small organic molecule |
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| Emp. Form. | C55H59BClF2N9O7S3 |
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| Mol. Mass. | 1138.569 |
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| SMILES | Cn1cc(C2c3nc(NCCC(=O)NCCOCCOCCNC(=O)CCCCCNC(=O)COc4ccc(\C=C\C5=[N+]6C(Cc7ccc(-c8cccs8)n7[B-]6(F)F)C=C5)cc4)sc3C=Cc3cc(Cl)ccc23)c(=S)[nH]c1=O |c:61,70,t:41| |
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| Structure | 
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