| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50014145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_159470 (CHEMBL769256) |
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| IC50 | 0.220000±n/a nM |
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| Citation |  Kempf, DJ; Norbeck, DW; Codacovi, L; Wang, XC; Kohlbrenner, WE; Wideburg, NE; Paul, DA; Knigge, MF; Vasavanonda, S; Craig-Kennard, A Structure-based, C2 symmetric inhibitors of HIV protease. J Med Chem33:2687-9 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
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| BDBM50014145 |
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| n/a |
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| Name | BDBM50014145 |
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| Synonyms: | CHEMBL314298 | {1-[1-Benzyl-4-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-2,3-dihydroxy-5-phenyl-pentylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C44H54N4O8 |
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| Mol. Mass. | 766.9216 |
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| SMILES | CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)OCc1ccccc1)C(C)C |
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| Structure | 
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