| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM50274047 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1713682 (CHEMBL4123731) |
|---|
| Ki | 0.050±n/a nM |
|---|
| Citation |  Zhou, J; Stapleton, P; Haider, S; Healy, J Boronic acid inhibitors of the class A?-lactamase KPC-2. Bioorg Med Chem26:2921-2927 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
|---|
| Type: | Protien |
|---|
| Mol. Mass.: | 41561.62 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P00811 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
|
|
|
|---|
| BDBM50274047 |
|---|
| n/a |
|---|
| Name | BDBM50274047 |
|---|
| Synonyms: | CHEMBL3613796 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H9BF3N5O4S |
|---|
| Mol. Mass. | 351.07 |
|---|
| SMILES | OB(O)CNS(=O)(=O)c1ccc(cc1C(F)(F)F)-c1nnn[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
