| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsin-like elastase family member 1 |
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| Ligand | BDBM50014734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_63628 |
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| Ki | 660.0±n/a nM |
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| Citation |  Peet, NP; Burkhart, JP; Angelastro, MR; Giroux, EL; Mehdi, S; Bey, P; Kolb, M; Neises, B; Schirlin, D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem33:394-407 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsin-like elastase family member 1 |
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| Name: | Chymotrypsin-like elastase family member 1 |
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| Synonyms: | CELA1 | CELA1_HUMAN | ELA1 | Elastase 1 | Elastase-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27805.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_63626 |
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| Residue: | 258 |
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| Sequence: | MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
FTQVSAYISWINNVIASN
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| BDBM50014734 |
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| n/a |
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| Name | BDBM50014734 |
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| Synonyms: | CHEMBL132768 | N-{1-Benzyl-2-oxo-2-[2-(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-pyrrolidin-1-yl]-ethyl}-succinamic acid methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32F3N3O6 |
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| Mol. Mass. | 527.5333 |
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| SMILES | COC(=O)CCC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F |
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| Structure | 
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