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TargetElastase 1
LigandBDBM50014734
Substrate/Competitorn/a
Meas. Tech.ChEBML_63628
Ki 660.0±n/a nM
Citation Peet NPBurkhart JPAngelastro MRGiroux ELMehdi SBey PKolb MNeises BSchirlin D Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G. J Med Chem 33:394-407 (1990) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Elastase 1
Name:Elastase 1
Synonyms:Elastase-1
Type:PROTEIN
Mol. Mass.:27805.35
Organism:Homo sapiens (Human)
Description:ChEMBL_63626
Residue:258
Sequence:
MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
FTQVSAYISWINNVIASN
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  Blast E-value cutoff:
BDBM50014734
n/a
NameBDBM50014734
Synonyms:CHEMBL132768 | N-{1-Benzyl-2-oxo-2-[2-(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-pyrrolidin-1-yl]-ethyl}-succinamic acid methyl ester
TypeSmall organic molecule
Emp. Form.C25H32F3N3O6
Mol. Mass.527.5333
SMILESCOC(=O)CCC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F
Structure
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