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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 2 | ||
| Ligand | BDBM50278411 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1720163 (CHEMBL4135163) | ||
| IC50 | 6770±n/a nM | ||
| Citation |  Ji, YY; Lin, SD; Wang, YJ; Su, MB; Zhang, W; Gunosewoyo, H; Yang, F; Li, J; Tang, J; Zhou, YB; Yu, LF Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors. Eur J Med Chem141:101-112 (2017) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 2 | |||
| Name: | Lysine-specific histone demethylase 2 | ||
| Synonyms: | AOF1 | C6orf193 | Flavin-containing amine oxidase domain-containing protein 1 | KDM1B | KDM1B_HUMAN | LSD2 | Lysine-specific histone demethylase 1B | Lysine-specific histone demethylase 2 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 92112.91 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_992590 | ||
| Residue: | 822 | ||
| Sequence: |
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| BDBM50278411 | |||
| n/a | |||
| Name | BDBM50278411 | ||
| Synonyms: | CHEMBL4170367 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H23ClN2 | ||
| Mol. Mass. | 278.82 | ||
| SMILES | Cl.[H][C@]12Cc3ccccc3[C@@]1([H])[C@@]2([H])N[C@H]1CC[C@H](N)CC1 |r,wU:18.20,wD:10.11,2.0,15.16,12.14,(38.29,-9.18,;30.02,-9.7,;28.54,-9.31,;27.64,-10.57,;26.17,-10.09,;24.84,-10.87,;23.5,-10.1,;23.5,-8.55,;24.83,-7.78,;26.17,-8.54,;27.63,-8.06,;27.62,-6.52,;29.16,-7.91,;30.49,-8.67,;30.41,-7,;31.75,-7.74,;31.78,-9.28,;33.11,-10.02,;34.43,-9.23,;35.77,-9.98,;34.4,-7.7,;33.06,-6.95,)| | ||
| Structure | 
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