| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50281818 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1722913 (CHEMBL4137913) |
|---|
| Ki | 33±n/a nM |
|---|
| Citation |  Weiss, DR; Karpiak, J; Huang, XP; Sassano, MF; Lyu, J; Roth, BL; Shoichet, BK Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets. J Med Chem61:6830-6845 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
|---|
| Type: | undefined |
|---|
| Mol. Mass.: | 52607.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P28223 |
|---|
| Residue: | 471 |
|---|
| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
|
|
|
|---|
| BDBM50281818 |
|---|
| n/a |
|---|
| Name | BDBM50281818 |
|---|
| Synonyms: | CHEMBL3461530 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H27N5O |
|---|
| Mol. Mass. | 341.4506 |
|---|
| SMILES | Cc1[nH]ncc1C(=O)NCCCN1CCN(CC1)c1cccc(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
