| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50283955 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1726373 (CHEMBL4141651) |
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| Ki | >10000±n/a nM |
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| Citation |  Jorgensen, WT; Gulliver, DW; Katte, TA; Werry, EL; Reekie, TA; Connor, M; Kassiou, M Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors. Eur J Med Chem143:1644-1656 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42793.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Oxytocin OXTR HEK293::B2R9L7 |
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| Residue: | 389 |
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| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
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| BDBM50283955 |
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| n/a |
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| Name | BDBM50283955 |
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| Synonyms: | CHEMBL4169437 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H38N6O3 |
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| Mol. Mass. | 566.6932 |
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| SMILES | COc1cc(CN2CCN(CC2)c2ccc(CCC(=O)N3Cc4cnn(C)c4Nc4ccccc34)cc2)cc(OC)c1 |
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| Structure | 
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