| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50283972 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1726374 (CHEMBL4141652) |
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| Ki | 643±n/a nM |
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| Citation |  Jorgensen, WT; Gulliver, DW; Katte, TA; Werry, EL; Reekie, TA; Connor, M; Kassiou, M Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors. Eur J Med Chem143:1644-1656 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM50283972 |
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| n/a |
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| Name | BDBM50283972 |
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| Synonyms: | CHEMBL4162565 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H32N6O3 |
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| Mol. Mass. | 524.6135 |
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| SMILES | Cn1ncc2CN(C(=O)Cc3cccc(c3)N3CCN(Cc4cc(O)cc(O)c4)CC3)c3ccccc3Nc12 |
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| Structure | 
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