| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 |
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| Ligand | BDBM50016595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32070 (CHEMBL645981) |
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| IC50 | 128000±n/a nM |
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| Citation |  DeRuiter, J; Swearingen, BE; Wandrekar, V; Mayfield, CA Synthesis and in vitro aldose reductase inhibitory activity of compounds containing an N-acylglycine moiety. J Med Chem32:1033-8 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldo-keto reductase family 1 member B1 |
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| Name: | Aldo-keto reductase family 1 member B1 |
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| Synonyms: | ALDR_RAT | Akr1b1 | Akr1b4 | Aldose reductase | Aldr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35797.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1512484 |
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| Residue: | 316 |
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| Sequence: | MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ
EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP
DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP
AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK
YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV
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| BDBM50016595 |
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| n/a |
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| Name | BDBM50016595 |
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| Synonyms: | 2-(Acetyl-p-tolyl-amino)-propionic acid | CHEMBL276222 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15NO3 |
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| Mol. Mass. | 221.2524 |
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| SMILES | CC(N(C(C)=O)c1ccc(C)cc1)C(O)=O |
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| Structure | 
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