| Reaction Details |
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 | Report a problem with these data |
| Target | NAD(P)H dehydrogenase [quinone] 1 |
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| Ligand | BDBM50316155 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1733843 (CHEMBL4149379) |
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| Ki | 450±n/a nM |
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| Citation |  Zhang, K; Chen, D; Ma, K; Wu, X; Hao, H; Jiang, S NAD(P)H:Quinone Oxidoreductase 1 (NQO1) as a Therapeutic and Diagnostic Target in Cancer. J Med Chem61:6983-7003 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| NAD(P)H dehydrogenase [quinone] 1 |
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| Name: | NAD(P)H dehydrogenase [quinone] 1 |
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| Synonyms: | Azoreductase | DIA4 | DT-diaphorase | Menadione reductase | NAD(P)H:quinone oxidoreductase 1 | NMOR1 | NQO1 | NQO1_HUMAN | Phylloquinone reductase | QR1 | Quinone Reductase 1 | Quinone reductase 1) |
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| Type: | Homodimer |
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| Mol. Mass.: | 30874.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 274 |
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| Sequence: | MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
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| BDBM50316155 |
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| n/a |
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| Name | BDBM50316155 |
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| Synonyms: | CHEMBL357217 | ES-936 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N2O6 |
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| Mol. Mass. | 356.3294 |
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| SMILES | COC1=CC(=O)c2c(c(COc3ccc(cc3)[N+]([O-])=O)c(C)n2C)C1=O |t:2| |
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| Structure | 
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