| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5B, mitochondrial |
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| Ligand | BDBM50341391 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1734318 (CHEMBL4149854) |
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| Ki | 5.5±n/a nM |
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| Citation |  Angeli, A; di Cesare Mannelli, L; Trallori, E; Peat, TS; Ghelardini, C; Carta, F; Supuran, CT Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology. ACS Med Chem Lett9:462-467 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5B, mitochondrial |
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| Name: | Carbonic anhydrase 5B, mitochondrial |
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| Synonyms: | CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36440.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 317 |
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| Sequence: | MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
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| BDBM50341391 |
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| n/a |
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| Name | BDBM50341391 |
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| Synonyms: | CHEMBL4163634 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13NO3SSe |
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| Mol. Mass. | 294.23 |
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| SMILES | [#6]-[#8]-[#6]-[#6][Se;v2]c1ccc(cc1)S([#7])(=O)=O |
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| Structure | 
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