Reaction Details |
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Target | Complement factor D |
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Ligand | BDBM50331395 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1734432 (CHEMBL4149968) |
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Kd | >2000000±n/a nM |
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Citation | Vulpetti, A; Ostermann, N; Randl, S; Yoon, T; Mac Sweeney, A; Cumin, F; Lorthiois, E; Rüdisser, S; Erbel, P; Maibaum, J Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D. ACS Med Chem Lett9:490-495 (2018) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Complement factor D |
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Name: | Complement factor D |
Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
Type: | Protein |
Mol. Mass.: | 27039.19 |
Organism: | Homo sapiens (Human) |
Description: | P00746 |
Residue: | 253 |
Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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BDBM50331395 |
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n/a |
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Name | BDBM50331395 |
Synonyms: | CHEMBL4162063 |
Type | Small organic molecule |
Emp. Form. | C13H13N |
Mol. Mass. | 183.249 |
SMILES | NCc1cccc(c1)-c1ccccc1 |
Structure |
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