| Reaction Details |
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 | Report a problem with these data |
| Target | Complement factor D |
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| Ligand | BDBM50330412 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1734433 (CHEMBL4149969) |
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| Kd | 80000±n/a nM |
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| Citation |  Vulpetti, A; Ostermann, N; Randl, S; Yoon, T; Mac Sweeney, A; Cumin, F; Lorthiois, E; Rüdisser, S; Erbel, P; Maibaum, J Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D. ACS Med Chem Lett9:490-495 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Complement factor D |
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| Name: | Complement factor D |
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| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
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| Type: | Protein |
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| Mol. Mass.: | 27039.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00746 |
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| Residue: | 253 |
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| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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| BDBM50330412 |
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| n/a |
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| Name | BDBM50330412 |
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| Synonyms: | CHEMBL4161222 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N2O |
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| Mol. Mass. | 356.4602 |
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| SMILES | NCc1cccc(c1)-c1cccc(c1)C(=O)N[C@@H]1CCCc2ccccc12 |r| |
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| Structure | 
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