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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1A) dopamine receptor | ||
| Ligand | BDBM50004823 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_58666 | ||
| Ki | 1.9±n/a nM | ||
| Citation |  Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Synthesis and receptor affinities of some conformationally restricted analogues of the dopamine D1 selective ligand (5R)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl- 1H-3-benzazepin-7-ol. J Med Chem32:1913-21 (1989) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1A) dopamine receptor | |||
| Name: | D(1A) dopamine receptor | ||
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 49429.75 | ||
| Organism: | RAT | ||
| Description: | P18901 | ||
| Residue: | 446 | ||
| Sequence: |
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| BDBM50004823 | |||
| n/a | |||
| Name | BDBM50004823 | ||
| Synonyms: | (6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | (6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol | 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | CHEMBL298406 | Ecopipam | SCH 39166 | trans-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H20ClNO | ||
| Mol. Mass. | 313.821 | ||
| SMILES | CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 | ||
| Structure | 
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