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TargetStromal cell-derived factor 1
LigandBDBM50369316
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1736458 (CHEMBL4151994)
Ki>10000±n/a nM
Citation Regenass, PAbboud, DDaubeuf, FLehalle, CGizzi, PRiché, SHachet-Haas, MRohmer, FGasparik, VBoeglin, DHaiech, JKnehans, TRognan, DHeissler, DMarsol, CVilla, PGalzi, JLHibert, MFrossard, NBonnet, D Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. J Med Chem61:7671-7686 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Stromal cell-derived factor 1
Name:Stromal cell-derived factor 1
Synonyms:CXCL12 | Chemokine CXCL12 | SDF1 | SDF1A | SDF1B | SDF1_HUMAN
Type:Enzyme
Mol. Mass.:10677.83
Organism:Homo sapiens (Human)
Description:P48061
Residue:93
Sequence:
MNAKVVVVLVLVLTALCLSDGKPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIV
ARLKNNNRQVCIDPKLKWIQEYLEKALNKRFKM
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BDBM50369316
n/a
NameBDBM50369316
Synonyms:CHEMBL4166202
TypeSmall organic molecule
Emp. Form.C16H15ClO3
Mol. Mass.290.742
SMILESCOc1cc(CCC(=O)c2ccc(Cl)cc2)ccc1O
Structure
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