| Reaction Details |
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 | Report a problem with these data |
| Target | N-arachidonyl glycine receptor |
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| Ligand | BDBM50056486 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1740206 (CHEMBL4155956) |
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| EC50 | 20±n/a nM |
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| Citation |  Schoeder, CT; Kaleta, M; Mahardhika, AB; Olejarz-Maciej, A; ?a?ewska, D; Kie?-Kononowicz, K; Müller, CE Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18. Eur J Med Chem155:381-397 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-arachidonyl glycine receptor |
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| Name: | N-arachidonyl glycine receptor |
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| Synonyms: | G-protein coupled receptor 18 | GPCRW | GPR18 | GPR18_HUMAN | NAGly receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38150.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107601 |
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| Residue: | 331 |
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| Sequence: | MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY
MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY
MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY
LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ
VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV
MLYRNYLRSMRRKSFRSGSLRSLSNINSEML
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| BDBM50056486 |
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| n/a |
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| Name | BDBM50056486 |
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| Synonyms: | ((5Z,8Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic acid | ((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoylamino)-acetic acid | Arachidonoyl glycine | CHEMBL161343 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H35NO3 |
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| Mol. Mass. | 361.5182 |
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| SMILES | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC(O)=O |
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| Structure | 
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