| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 2 |
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| Ligand | BDBM23120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1743315 (CHEMBL4177825) |
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| IC50 | 13±n/a nM |
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| Citation |  Tuo, W; Leleu-Chavain, N; Spencer, J; Sansook, S; Millet, R; Chavatte, P Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors. J Med Chem60:4-46 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 2 |
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| Name: | Fatty-acid amide hydrolase 2 |
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| Synonyms: | AMDD | Amidase domain-containing protein | Anandamide amidohydrolase 2 | FAAH2 | FAAH2_HUMAN | Oleamide hydrolase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58325.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_857738 |
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| Residue: | 532 |
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| Sequence: | MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLI
RQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENK
WPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELC
MWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGI
FGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKV
HLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLW
IAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRY
SNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSAL
GLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF
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| BDBM23120 |
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| n/a |
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| Name | BDBM23120 |
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| Synonyms: | 7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptan-1-one | CHEMBL177577 | OL-135 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N2O2 |
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| Mol. Mass. | 334.4116 |
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| SMILES | O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 |
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| Structure | 
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