| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase |
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| Ligand | BDBM5231 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1751542 (CHEMBL4186302) |
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| IC50 | 85±n/a nM |
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| Citation |  Wang, Z; Cheng, LP; Zhang, XH; Pang, W; Li, L; Zhao, JL Design, synthesis and biological evaluation of novel oseltamivir derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett27:5429-5435 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase |
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| Name: | Sialidase |
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| Synonyms: | NANH_CLOPF | nanH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42808.79 |
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| Organism: | Clostridium perfringens |
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| Description: | ChEMBL_991336 |
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| Residue: | 382 |
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| Sequence: | MCNKNNTFEKNLDISHKPEPLILFNKDNNIWNSKYFRIPNIQLLNDGTILTFSDIRYNGP
DDHAYIDIASARSTDFGKTWSYNIAMKNNRIDSTYSRVMDSTTVITNTGRIILIAGSWNT
NGNWAMTTSTRRSDWSVQMIYSDDNGLTWSNKIDLTKDSSKVKNQPSNTIGWLGGVGSGI
VMDDGTIVMPAQISLRENNENNYYSLIIYSKDNGETWTMGNKVPNSNTSENMVIELDGAL
IMSTRYDYSGYRAAYISHDLGTTWEIYEPLNGKILTGKGSGCQGSFIKATTSNGHRIGLI
SAPKNTKGEYIRDNIAVYMIDFDDLSKGVQEICIPYPEDGNKLGGGYSCLSFKNNHLGIV
YEANGNIEYQDLTPYYSLINKQ
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| BDBM5231 |
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| n/a |
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| Name | BDBM5231 |
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| Synonyms: | (3R,4R,5S)-5-amino-3-[butyl(ethyl)amino]-4-acetamidocyclohex-1-ene-1-carboxylic acid | C3-Aza Carbocyclic Analogue 3g |
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| Type | Small organic molecule |
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| Emp. Form. | C15H27N3O3 |
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| Mol. Mass. | 297.3932 |
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| SMILES | CCCCN(CC)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:8| |
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| Structure | 
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