| Reaction Details |
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 | Report a problem with these data |
| Target | Lipopolysaccharide heptosyltransferase 1 |
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| Ligand | BDBM228805 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1753351 (CHEMBL4188111) |
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| Ki | 500000±n/a nM |
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| Citation |  Nkosana, NK; Czyzyk, DJ; Siegel, ZS; Cote, JM; Taylor, EA Synthesis, kinetics and inhibition of Escherichia coli Heptosyltransferase I by monosaccharide analogues of Lipid A. Bioorg Med Chem Lett28:594-600 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lipopolysaccharide heptosyltransferase 1 |
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| Name: | Lipopolysaccharide heptosyltransferase 1 |
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| Synonyms: | 2.-.-.- | Lipopolysaccharide heptosyltransferase 1 | RFAC_ECOLI | rfa-2 | rfaC | waaC | yibC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35553.92 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_117821 |
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| Residue: | 319 |
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| Sequence: | MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQIPSWHAAVERVIPVAIR
RWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAR
EPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQGDYAIAQHFLTNLPTDAGEY
AVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFAYVEVLP
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGKNQMVCRAP
RENLINLNSQAVLEKLSSL
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| BDBM228805 |
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| n/a |
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| Name | BDBM228805 |
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| Synonyms: | Galactose |
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| Type | Small organic molecule |
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| Emp. Form. | C6H12O6 |
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| Mol. Mass. | 180.1559 |
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| SMILES | OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O |
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| Structure | 
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