| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM319796 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1758530 (CHEMBL4193538) |
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| IC50 | 9.0±n/a nM |
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| Citation |  Li, Y; Chen, Q; Yang, L; Li, Y; Zhang, Y; Qiu, Y; Ren, J; Lu, C Identification of highly potent N-acylethanolamine acid amidase (NAAA) inhibitors: Optimization of the terminal phenyl moiety of oxazolidone derivatives. Eur J Med Chem139:214-221 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | Asahl | N-acylethanolamine acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase | N-acylethanolamine-hydrolyzing acid amidase (NAAA) | N-acylethanolamine-hydrolyzing acid amidase subunit alpha | N-acylethanolamine-hydrolyzing acid amidase subunit beta | N-acylsphingosine amidohydrolase-like | NAAA_RAT | Naaa |
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| Type: | Enzyme |
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| Mol. Mass.: | 40306.53 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q5KTC7 |
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| Residue: | 362 |
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| Sequence: | MGTPAIRAACHGAHLALALLLLLSLSDPWLWATAPGTPPLFNVSLDAAPELRWLPMLQHY
DPDFVRAAVAQVIGDRVPQWILEMIGEIVQKVESFLPQPFTSEIRGICDYLNLSLAEGVL
VNLAYEASAFCTSIVAQDSQGRIYHGRNLDYPFGNALRKLTADVQFVKNGQIVFTATTFV
GYVGLWTGQSPHKFTISGDERDKGWWWENMIAALSLGHSPISWLIRKTLTESEDFEAAVY
TLAKTPLIADVYYIVGGTSPQEGVVITRDRGGPADIWPLDPLNGAWFRVETNYDHWEPVP
KRDDRRTPAIKALNATGQAHLSLETLFQVLSVFPVYNNYTIYTTVMSAAEPDKYMTMIRN
PS
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| BDBM319796 |
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| n/a |
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| Name | BDBM319796 |
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| Synonyms: | US10174015, Compound 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18ClNO3 |
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| Mol. Mass. | 295.761 |
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| SMILES | Clc1cccc(CCCCCC(=O)N2CCOC2=O)c1 |
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| Structure | 
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