| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50458557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1764147 (CHEMBL4199394) |
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| EC50 | 41±n/a nM |
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| Citation |  Kim, Y; Kim, H; Lee, J; Lee, JK; Min, SJ; Seong, J; Rhim, H; Tae, J; Lee, HJ; Choo, H Discovery of ?-Arrestin Biased Ligands of 5-HT J Med Chem61:7218-7233 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50458557 |
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| n/a |
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| Name | BDBM50458557 |
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| Synonyms: | CHEMBL4215875 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N2O |
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| Mol. Mass. | 228.2896 |
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| SMILES | Cc1ccc(cc1)-c1noc2CCNCCc12 |
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| Structure | 
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