| Reaction Details |
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 | Report a problem with these data |
| Target | Group 10 secretory phospholipase A2 |
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| Ligand | BDBM50458606 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1764262 (CHEMBL4199509) |
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| IC50 | 65±n/a nM |
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| Citation |  Giordanetto, F; Knerr, L; Nordberg, P; Pettersen, D; Selmi, N; Beisel, HG; de la Motte, H; Månsson, Å; Dahlström, M; Broddefalk, J; Saarinen, G; Klingegård, F; Hurt-Camejo, E; Rosengren, B; Wikström, J; Wågberg, M; Brengdahl, J; Rohman, M; Sandmark, J; Åkerud, T; Roth, RG; Jansen, F; Ahlqvist, M Design of Selective sPLA ACS Med Chem Lett9:600-605 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group 10 secretory phospholipase A2 |
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| Name: | Group 10 secretory phospholipase A2 |
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| Synonyms: | Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18153.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1442449 |
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| Residue: | 165 |
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| Sequence: | MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPI
AYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGP
AENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
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| BDBM50458606 |
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| n/a |
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| Name | BDBM50458606 |
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| Synonyms: | CHEMBL4205511 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16F3N3O4 |
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| Mol. Mass. | 407.3432 |
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| SMILES | CC(Cc1cccc(n1)-n1c(cc2ccc(OC(F)(F)F)cc12)C(N)=O)C(O)=O |
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| Structure | 
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