| Reaction Details |
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 | Report a problem with these data |
| Target | Group 10 secretory phospholipase A2 |
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| Ligand | BDBM50366784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1764267 (CHEMBL4199514) |
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| IC50 | 310±n/a nM |
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| Citation |  Giordanetto, F; Knerr, L; Nordberg, P; Pettersen, D; Selmi, N; Beisel, HG; de la Motte, H; Månsson, Å; Dahlström, M; Broddefalk, J; Saarinen, G; Klingegård, F; Hurt-Camejo, E; Rosengren, B; Wikström, J; Wågberg, M; Brengdahl, J; Rohman, M; Sandmark, J; Åkerud, T; Roth, RG; Jansen, F; Ahlqvist, M Design of Selective sPLA ACS Med Chem Lett9:600-605 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Group 10 secretory phospholipase A2 |
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| Name: | Group 10 secretory phospholipase A2 |
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| Synonyms: | Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18153.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1442449 |
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| Residue: | 165 |
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| Sequence: | MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPI
AYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGP
AENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
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| BDBM50366784 |
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| n/a |
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| Name | BDBM50366784 |
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| Synonyms: | CHEMBL4171084 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15F3N2O4 |
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| Mol. Mass. | 392.3286 |
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| SMILES | NC(=O)c1cc2ccc(OC(F)(F)F)cc2n1-c1cccc(CCC(O)=O)c1 |
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| Structure | 
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