| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A-5 |
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| Ligand | BDBM50022510 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153847 (CHEMBL882425) |
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| pH | 3.1±n/a |
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| IC50 | 6±n/a nM |
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| Comments | extracted |
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| Citation |  Maibaum, J; Rich, DH Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases. J Med Chem31:625-9 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Pepsin A-5 |
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| Name: | Pepsin A-5 |
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| Synonyms: | PEPA5_HUMAN | PGA5 | Pepsin A | Pepsinogen A5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41971.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1452206 |
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| Residue: | 388 |
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| Sequence: | MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNVPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
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| BDBM50022510 |
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| n/a |
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| Name | BDBM50022510 |
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| Synonyms: | Boc-Phe-His-Leu-CF3-Ile-Amp | CHEMBL154795 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H54F2N8O7 |
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| Mol. Mass. | 796.903 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)C(F)(F)C(=O)C(CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccn1 |
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| Structure | 
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