| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A |
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| Ligand | BDBM50022523 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154012 (CHEMBL759133) |
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| pH | 4±n/a |
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| Ki | 40000±n/a nM |
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| Comments | extracted |
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| Citation |  Maibaum, J; Rich, DH Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases. J Med Chem31:625-9 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pepsin A |
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| Name: | Pepsin A |
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| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41232.87 |
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| Organism: | Porcine |
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| Description: | n/a |
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| Residue: | 385 |
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| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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| BDBM50022523 |
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| n/a |
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| Name | BDBM50022523 |
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| Synonyms: | CHEMBL347185 | H2N-Phe-Gly-His-Nph-Phe-Ala-Phe-OMe |
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| Type | Small organic molecule |
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| Emp. Form. | C48H54N10O10 |
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| Mol. Mass. | 931.0034 |
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| SMILES | COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](N)Cc1ccccc1 |
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| Structure | 
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