| Reaction Details |
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 | Report a problem with these data |
| Target | Pepsin A |
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| Ligand | BDBM50022862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_153986 |
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| IC50 | >10000±n/a nM |
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| Citation |  Sham, HL; Bolis, G; Stein, HH; Fesik, SW; Marcotte, PA; Plattner, JJ; Rempel, CA; Greer, J Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen. J Med Chem31:284-95 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Pepsin A |
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| Name: | Pepsin A |
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| Synonyms: | PEPA_PIG | PGA | Pepsin | Pepsin A precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41232.87 |
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| Organism: | Porcine |
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| Description: | n/a |
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| Residue: | 385 |
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| Sequence: | MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALI
GDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDS
STFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGIL
GLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNW
VPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENS
DGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWIL
GDVFIRQYYTVFDRANNKVGLAPVA
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| BDBM50022862 |
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| n/a |
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| Name | BDBM50022862 |
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| Synonyms: | Boc-Phe-Ala-Leu-Val-Ile-His-OMe | CHEMBL101874 |
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| Type | Small organic molecule |
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| Emp. Form. | C41H64N8O9 |
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| Mol. Mass. | 812.9951 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)OC |
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| Structure | 
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